Cesar V. Borlongan
Session: Plenary Lecture 4
Date: May 6th, 2020
Time: 13:40 to 14:30
Venue: 201 Meeting Room
Language: English
Cesar V. Borlongan
A. Personal Statement
I serve as the Principal Investigator of research projects designed to demonstrate the safety and efficacy, as well
as mechanisms of action underlying novel neuroprotective and neurorestorative therapies in brain injury,
resonating my long-standing efforts in the advancement of experimental therapies for neurological disorders from
the laboratory to the clinic. My PI role in these projects dovetails into my status as a world leader in cell therapy,
with my highly innovative translational “bench to clinic” research providing the IND enabling studies for 5 FDAapproved
clinical trials of stem cell transplantation in stroke, TBI, and cerebral palsy. Since completing an
NIH Staff Fellowship and joining the academe in 2002, I have received continuous multiple federal funding from
the VA, DoD, and NIH. I am an author of more than 450 peer-reviewed publications and lead editor of 2 books,
and serve as editor-in-chief, section editor and/or editorial board member of many scientific journals. I have
served regularly as a study section member of NIH NOMD, NIH NSD-A, and VA NURE, and have served as
chair and reviewer of other various national (e.g., AHA) and international funding agencies. In summary, I
have a demonstrated track record of successful and productive research projects in an area of high relevance
for biomedical therapeutic research and development, and my expertise and experience have prepared me to
serve as PI of currently funded and pending research projects.
1. Borlongan, C.V., & Sanberg, P.R. Elevated body swing test: A new behavioral parameter for rats with 6-
hydroxydopamine-induced hemiparkinsonism. Journal of Neuroscience, 15:5372-5378, 1995. PMID:
7623159
2. Borlongan, C.V., Sanberg, P.R., & Freeman, T.B. Neural transplantation for neurodegenerative disorders. The
Lancet, 353:129-130, 1999. PMID:10319932
3. Freeman, T.B., Olanow, C.W., Hauser, R.A., Nauert, G. M., Smith, D.A., Borlongan, C.V., Sanberg, P.R.,
Snow, B.,Vingerhoets, F.J.G., Calne, D., & Gauger, L.L. Bilateral fetal nigral transplantation into the
postcommisural putamen as a treatment for Parkinson's disease: Six month follow-up. Annals of Neurology,
38:379-388, 1995. PMID: 7668823
4. Yasuhara T, Matsukawa N, Hara K, Yu G, Xu L, Maki M, Kim SU, Borlongan, C.V. Transplantation of human
neural stem cells exerts neuroprotection in a rat model of Parkinson's disease. Journal of Neuroscience,
26(48):12497-511. PubMed PMID: 17135412.
B. Positions and Honors
2011-Present Academic Editor, PLoS One
2012-Present Editorial Board Member, Journal of Cerebral Blood Flow and Metabolism
2012-Present Elected, Fellow of the American Academy for the Advancement of Science
2014-Present Editorial Board Member, International Journal of Molecular Sciences
2014-Present Editorial Board Member, Stroke
2015-2016 President, American Society for Neural Transplantation and Repair
2016-Present Elected, Fellow of the American Institute for Medical and Biological Engineering
2017 Supervisor of the Year, University of South Florida
2017 Everfront Most Outstanding Stem Cell Awardee, Pan Pacific Symposium on Stem Cells and Cancer
2017 USF World Global Achievement Faculty Award
2018-2022 Regular Study Section Member, NIH NSD-A, Neurological Sciences and Disorders A
Date: May 6th, 2020
Time: 13:40 to 14:30
Venue: 201 Meeting Room
Language: English
Cesar V. Borlongan
A. Personal Statement
I serve as the Principal Investigator of research projects designed to demonstrate the safety and efficacy, as well
as mechanisms of action underlying novel neuroprotective and neurorestorative therapies in brain injury,
resonating my long-standing efforts in the advancement of experimental therapies for neurological disorders from
the laboratory to the clinic. My PI role in these projects dovetails into my status as a world leader in cell therapy,
with my highly innovative translational “bench to clinic” research providing the IND enabling studies for 5 FDAapproved
clinical trials of stem cell transplantation in stroke, TBI, and cerebral palsy. Since completing an
NIH Staff Fellowship and joining the academe in 2002, I have received continuous multiple federal funding from
the VA, DoD, and NIH. I am an author of more than 450 peer-reviewed publications and lead editor of 2 books,
and serve as editor-in-chief, section editor and/or editorial board member of many scientific journals. I have
served regularly as a study section member of NIH NOMD, NIH NSD-A, and VA NURE, and have served as
chair and reviewer of other various national (e.g., AHA) and international funding agencies. In summary, I
have a demonstrated track record of successful and productive research projects in an area of high relevance
for biomedical therapeutic research and development, and my expertise and experience have prepared me to
serve as PI of currently funded and pending research projects.
1. Borlongan, C.V., & Sanberg, P.R. Elevated body swing test: A new behavioral parameter for rats with 6-
hydroxydopamine-induced hemiparkinsonism. Journal of Neuroscience, 15:5372-5378, 1995. PMID:
7623159
2. Borlongan, C.V., Sanberg, P.R., & Freeman, T.B. Neural transplantation for neurodegenerative disorders. The
Lancet, 353:129-130, 1999. PMID:10319932
3. Freeman, T.B., Olanow, C.W., Hauser, R.A., Nauert, G. M., Smith, D.A., Borlongan, C.V., Sanberg, P.R.,
Snow, B.,Vingerhoets, F.J.G., Calne, D., & Gauger, L.L. Bilateral fetal nigral transplantation into the
postcommisural putamen as a treatment for Parkinson's disease: Six month follow-up. Annals of Neurology,
38:379-388, 1995. PMID: 7668823
4. Yasuhara T, Matsukawa N, Hara K, Yu G, Xu L, Maki M, Kim SU, Borlongan, C.V. Transplantation of human
neural stem cells exerts neuroprotection in a rat model of Parkinson's disease. Journal of Neuroscience,
26(48):12497-511. PubMed PMID: 17135412.
B. Positions and Honors
2011-Present Academic Editor, PLoS One
2012-Present Editorial Board Member, Journal of Cerebral Blood Flow and Metabolism
2012-Present Elected, Fellow of the American Academy for the Advancement of Science
2014-Present Editorial Board Member, International Journal of Molecular Sciences
2014-Present Editorial Board Member, Stroke
2015-2016 President, American Society for Neural Transplantation and Repair
2016-Present Elected, Fellow of the American Institute for Medical and Biological Engineering
2017 Supervisor of the Year, University of South Florida
2017 Everfront Most Outstanding Stem Cell Awardee, Pan Pacific Symposium on Stem Cells and Cancer
2017 USF World Global Achievement Faculty Award
2018-2022 Regular Study Section Member, NIH NSD-A, Neurological Sciences and Disorders A